Season-Long Protection
Flu Season Timeline · Waning Coverage · Investigational Prophylactic Window
Even with 65% seasonal coverage in ≥65y, waning immunity leaves effective protection under 30% at peak season. Investigational Prophylactic's 24-week window covers 88% of the season's cases.
Flu Season, Waning Coverage, and Investigational Prophylactic Window
Week-of-year vs incidence, current vaccine effective protection, Investigational Prophylactic protection band
Vaccinate in October, effective protection peaks in November, wanes through Feb; Investigational Prophylactic (violet band) stays flat through the season.