Provenance
Data Sources & Calibration
Four tiers of evidence power this platform: public surveillance, real-world data, Investigational Prophylactic proprietary data, and live regulatory + literature intelligence.
Every number in this dashboard traces back to a source — either a PMID from the SLR, an aggregate from the real-world cohort, or a CDC / ClinicalTrials.gov / PubMed endpoint queried live. Click any PMID chip anywhere in the app to open the citation drawer.
Tier 1
LIVEPublic Surveillance
Sources
- • CDC FluView (weekly ILI activity)
- • CDC NSSP (ED visits, weekly)
- • CDC RESP-NET (age-stratified rates)
- • CDC WONDER (mortality)
- • WHO FluNet (global comparison)
- • CDC Disease Burden Estimates
Provides
incidencehospitalizationmortalityseasonality
Live status
CDC NSSP updated weekly
Powered by /surveillance
Tier 2
Real-World Data
Sources
- • IBM/Merative MarketScan (claims)
- • Optum Clinformatics DataMart
- • Komodo Health
- • CMS ResDAC / Medicare 100%
- • TriNetX EHR federation
- • Flatiron Oncology · COTA
Provides
high-risk populationscomorbiditiesHRU costsutilization
Tier 3
Proprietary Sponsor
Sources
- • Phase 2b readout
- • Phase 3 pivotal · Investigational Prophylactic
- • Future RWE post-launch
- • Internal HEOR modeling
Provides
Investigational Prophylactic efficacyduration of protectionsubgroup effectiveness
Tier 4
LIVERegulatory & Literature
Sources
- • ClinicalTrials.gov v2 API (NIH trial registry)
- • NCBI PubMed E-utilities (literature)
- • FDA Drug Approvals · CBER
- • IQVIA Citeline / Trialtrove (site landscape)
- • CDC Advisory Committee (ACIP)
Provides
trial pipelinesite landscapeKOL directorylive literature feed
Live status
ctgov + PubMed queried live
Powered by /trials & /evidence-tracker
SLR Corpus
Curated evidence library
US publications
111
Global publications
111
Clinical endpoints (US)
691
Economic endpoints (US)
223
Endpoints (global)
609
Provenance rows (audit)
5245
Window
2016–2026
Last updated
2026-07-09
Cohort Composition
N=50,000 patients · 40,422 flu episodes across 10 seasons
| Tier | N (patient-seasons) | Hosp / 100K | ICU % | Mortality % |
|---|---|---|---|---|
| T1a | 2,899 | 4001.4 | 34.5 | 8.6 |
| T1b | 6,941 | 1743.3 | 21.5 | 3.3 |
| T2 | 105,140 | 819.9 | 20.5 | 3.6 |
| T3 | 182,090 | 467.9 | 15.6 | 2.7 |
| None | 202,870 | 176.5 | 15.9 | 1.7 |